The Buffalo Bills head south to face the Miami Dolphins in one of the most anticipated divisional matchups of Week 10 in the 2025/26 NFL season. This AFC East clash carries major playoff implications, as both teams continue to battle for control of one of the toughest divisions in football.

The Bills come into this game relying on their explosive offense led by Josh Allen, paired with a defense that continues to rank among the league’s best in pressure and takeaways. Meanwhile, Miami’s speed-heavy attack — powered by Tua Tagovailoa, Tyreek Hill, and Jaylen Waddle — makes every drive a threat to break wide open. With both teams known for big-play potential, fans should expect fireworks in South Florida.

Here’s everything you need to know about this pivotal Bills vs Dolphins matchup — including kickoff details, where to watch, and betting insights.

BEO betting odds are showing Miami as narrow home favorites ::: Discover the latest Bet Entertainment Odds predictions for this market.

When is the Buffalo vs Miami game?
The Buffalo Bills will face the Miami Dolphins on Sunday, November 9, 2025, during Week 10 of the NFL regular season.

What Time Will the Game Start?
Kickoff is scheduled for 1:00 p.m. (ET) from Hard Rock Stadium in Miami Gardens, Florida.

Where Will It Be Held?
The game will be played at Hard Rock Stadium, home of the Miami Dolphins. Expect a loud, sun-soaked atmosphere as Miami looks to protect home turf against a rival that has given them problems in recent seasons.

Which Team is Favored to Win?
The Dolphins open as slight favorites thanks to their home-field edge and offensive versatility. Their ability to stretch the field vertically has been a difference-maker all season long, especially against defenses that struggle with elite speed.

The Bills, however, enter with a point to prove. Buffalo’s offense is capable of explosive momentum shifts, while their pass rush and secondary remain among the league’s most disruptive. If Josh Allen finds rhythm early, Buffalo could flip the script and take control of the AFC East race.

Where Can I Watch the Buffalo vs Miami game?
Fans can catch the action live on CBS or stream via Paramount+, NFL+, and FuboTV.

BEO Odds Insight
According to Bet Entertainment Odds, Miami opens as a -1.5 home favorite, with the total set at 47.5 points. Early bettors are split between both sides, but the Over is drawing attention due to both teams’ offensive firepower. Key prop lines include Tyreek Hill anytime TD (-115) and Josh Allen over 265.5 passing yards (-110).

Stay tuned with Bet Entertainment Odds for live odds movement, player prop updates, and expert analysis as the Bills and Dolphins renew their high-stakes AFC East rivalry in Miami.