The Atlanta Falcons head to Lucas Oil Stadium for an early Sunday showdown against the Indianapolis Colts in Week 10 of the 2025/26 NFL regular season. Both squads are entering a pivotal stretch of the year — Atlanta fighting to stay relevant in the NFC playoff picture, while Indianapolis continues to make noise in the AFC South race.

This inter-conference matchup brings an interesting contrast in play styles. The Falcons rely on a physical, run-heavy approach led by a balanced defense, while the Colts look to capitalize on their fast-paced, passing-focused offense inside their home dome. With both teams eyeing consistency and momentum, this one could shape the trajectory of their playoff hopes.

Here’s a complete preview of the Falcons vs Colts matchup — including kickoff details, broadcast info, and betting insights.

BEO betting odds have Indianapolis listed as slight home favorites ::: Check out the latest Bet Entertainment Odds predictions for this market.

When is the Atlanta vs Indianapolis game?
The Atlanta Falcons face the Indianapolis Colts on Sunday, November 9, 2025, as part of the early NFL schedule for Week 10.

What Time Will the Game Start?
Kickoff is set for 9:30 a.m. (ET), giving fans an early start to Sunday’s gridiron action.

Where Will It Be Held?
The game takes place at Lucas Oil Stadium in Indianapolis, Indiana — one of the league’s premier indoor venues, known for quick play and ideal offensive conditions.

Which Team is Favored to Win?
The Colts enter as slight favorites thanks to their improved quarterback performance and home-field advantage. Their protection up front has been solid, allowing them to sustain long drives and stay efficient on offense.

The Falcons, however, shouldn’t be underestimated. Their dominant rushing attack and physical defense make them a tough out on the road. If they control the clock and force turnovers, this matchup could tilt in their favor late in the game.

Where Can I Watch the Atlanta vs Indianapolis game?
Fans can tune in live on FOX or stream through NFL+ and FuboTV. International viewers can follow on DAZN NFL Game Pass.

BEO Odds Insight
According to Bet Entertainment Odds, the Colts open as -2.5 favorites, with the total set at 44.0 points. Early money is leaning toward Indianapolis on the spread, while sharp bettors are targeting the Under, expecting both defenses to dictate the pace. Player props drawing attention include Jonathan Taylor anytime TD (-110) and Bijan Robinson over 78.5 rushing yards (+105).

Stay locked in with Bet Entertainment Odds for real-time updates, sharp betting trends, and expert breakdowns as the Falcons and Colts square off in a critical midseason matchup.