The No. 1 Ohio State Buckeyes hit the road to take on the Purdue Boilermakers in a Week 11 Big Ten clash at Ross-Ade Stadium. The Buckeyes remain the team to beat in college football, boasting one of the most complete rosters in the nation — a high-powered offense and a relentless defensive front. Purdue, meanwhile, looks to play spoiler at home and pull off what would be one of the biggest upsets of the 2025 season.

Ohio State’s offense has been firing on all cylinders behind its elite quarterback play and dynamic receiving corps, while their defense has proven capable of shutting down both the run and the deep ball. Purdue will rely on creativity and tempo to find scoring opportunities, but their defense will face a major test trying to contain the Buckeyes’ balanced attack.

BEO betting odds are showing Ohio State as strong road favorites ::: Discover the latest Bet Entertainment Odds predictions for this market.

When is the Ohio State vs Purdue game?
The Ohio State Buckeyes face the Purdue Boilermakers on Saturday, November 8, 2025, during Week 11 of the NCAA Football season.

What Time Will the Game Start?
Kickoff is set for 1:00 p.m. (ET) at Ross-Ade Stadium in West Lafayette, Indiana.

Where Will It Be Held?
The matchup will be played at Ross-Ade Stadium, home of the Boilermakers. Purdue’s loyal fanbase will pack the stands, hoping their team can rise to the occasion against the No. 1-ranked Buckeyes in front of a national audience.

Which Team is Favored to Win?
The Buckeyes enter as -17.5 favorites, reflecting their dominance on both sides of the ball. Ohio State’s offensive line and deep receiving unit continue to overwhelm opponents, while their defensive consistency keeps them in control of nearly every matchup.

The Boilermakers will look to leverage home-field advantage and aggressive play-calling to keep the contest close early. For Purdue to stay competitive, they’ll need turnovers, long possessions, and big plays in the passing game to disrupt Ohio State’s rhythm.

Where Can I Watch the Ohio State vs Purdue game?
Fans can watch live on FOX and stream via FOX Sports App, FuboTV, and Hulu Live TV.

BEO Odds Insight
According to Bet Entertainment Odds, Ohio State opens as a -17.5 road favorite, with the total sitting at 55.0 points. Early betting trends show heavy public support for the Buckeyes, while sharp bettors are monitoring the Under, anticipating Ohio State’s defense to limit Purdue’s scoring chances. Key props include Ohio State QB over 2.5 passing touchdowns (-120) and Purdue to score under 20.5 points (-110).

Stay tuned with Bet Entertainment Odds for updated spreads, player props, and in-depth betting analysis as the top-ranked Buckeyes look to stay unbeaten against Purdue in this Big Ten showdown.