The No. 2 Indiana Hoosiers head to Beaver Stadium to take on the Penn State Nittany Lions in a pivotal Week 11 Big Ten matchup that could have major College Football Playoff implications. Indiana has been one of the surprise stories of the season, showcasing balance, discipline, and a confident defense that’s helped them rise to national prominence. Meanwhile, Penn State is looking to defend home turf and shake up the conference race with a statement win against one of the hottest teams in the country.

The Hoosiers’ efficient quarterback play and opportunistic defense have made them a tough opponent for anyone this season. Penn State, however, has the talent to keep things competitive — led by a versatile backfield and a defensive unit capable of generating pressure from multiple fronts. Expect a physical, grind-it-out battle between two programs that know each other well.

BEO betting odds are showing Indiana as slight road favorites ::: Discover the latest Bet Entertainment Odds predictions for this market.

When is the Indiana vs Penn State game?
The Indiana Hoosiers face the Penn State Nittany Lions on Saturday, November 8, 2025, as part of Week 11 of the 2025 NCAA Football season.

What Time Will the Game Start?
Kickoff is scheduled for 12:00 p.m. (ET) at Beaver Stadium in University Park, Pennsylvania.

Where Will It Be Held?
The matchup will take place at Beaver Stadium, one of the most iconic and intimidating venues in college football. Penn State’s home-field advantage and passionate fan base will make life difficult for any visiting team — even one ranked in the top 5.

Which Team is Favored to Win?
The Hoosiers enter as -4.5 favorites thanks to their strong two-way play and recent dominance within the Big Ten. Indiana’s ability to control tempo and limit turnovers has been key to their success.

The Nittany Lions, though, are never an easy out — especially at home. Their running game and defensive front have the tools to frustrate Indiana’s balanced offense and keep this one within reach deep into the fourth quarter.

Where Can I Watch the Indiana vs Penn State game?
Fans can watch the game live on FOX and stream it via FOX Sports App, FuboTV, or Hulu Live TV.

BEO Odds Insight
According to Bet Entertainment Odds, Indiana opens as a -4.5 favorite, with the total set at 48.5 points. Early public money leans toward Indiana on the spread, while sharps are watching the Under, expecting a defensive battle. Key player props include Indiana QB passing yards over 235.5 (-110) and Penn State RB anytime touchdown (+120).

Stay tuned with Bet Entertainment Odds for live market updates, player prop shifts, and expert analysis as the Hoosiers and Nittany Lions clash in a critical Big Ten showdown.