The Northwestern Wildcats will travel to face the No. 20-ranked USC Trojans in a highly anticipated Week 9 matchup of the 2025/26 NCAA Football regular season.

USC enters the contest ranked inside the Top 25 and will look to maintain their strong home record at the Los Angeles Memorial Coliseum. The Trojans’ explosive offense and depth at key positions make them favorites heading into the weekend. Meanwhile, Northwestern will aim to deliver a disciplined defensive performance and control possession in hopes of pulling off an upset on the road.

This Big Ten clash promises to be a compelling battle of strategy, execution, and momentum as both programs look to make a statement heading into November.

Here’s everything you need to know about the upcoming NCAA Football game between Northwestern and USC, including date, time, venue, and broadcast details.

BEO betting odds are showing USC as clear favorites at home ::: Discover the latest Bet Entertainment Odds predictions for this market.

When is the Northwestern vs USC game?

The Northwestern Wildcats will face the USC Trojans on Saturday, November 8, 2025, during Week 9 of the NCAA Football regular season.

What Time Will the Game Start?

Kick-off is scheduled for 7:00 p.m. (ET), corresponding to 4:00 p.m. local time in Los Angeles.

Where Will It Be Held?

The game will be played at the Los Angeles Memorial Coliseum in Los Angeles, California, one of college football’s most historic venues. The Trojans will look to use their home-field advantage to continue their push toward the postseason.

What Team is Most Likely to Win?

The USC Trojans enter the game as strong favorites, led by their high-powered offense and dynamic quarterback play. Their ability to stretch the field and dominate in the red zone could make the difference.

However, Northwestern brings a disciplined defense and a physical style of play that could slow the pace and test USC’s composure. If the Wildcats can control time of possession and limit big plays, they could make it a closer contest than expected.

Where Can I Watch the Northwestern vs USC game?

Fans in the United States can watch the game live on FOX Sports, ESPN, or stream it via FuboTV and ESPN+. International viewers can tune in through NCAA Game Pass or regional sports networks.

BEO Odds Insight

According to Bet Entertainment Odds, USC are heavy favorites to win at home, with strong action on Trojans to win and total points over 56.5. Prop bettors are targeting USC’s quarterback passing yards over 275.5 and Northwestern under 24.5 team points as key markets.

Visit Bet Entertainment Odds for updated lines, team props, and live in-play betting during the game.